WHOA! What's going on here? Who's this guy? Read more about him here: https://en.m.wikipedia.org/wiki/Steve_Mann_(inventor)
Digital endpoints can enhance signal detection
IQVIA SOMS is an example of a methodology developed to use AI in clinical research
Actigraph ™ Centerpoint System is an example of a passive data-collection method
Examples of sensors and digital measures/biomarkers
Digital 'biomarkers' derived from accelerometery (actigraphy). What we call a 'biomarker' in this case is somewhat dependent on use (i.e. the threshold for a regulatory authority would be higher than for a 2nd tier journal; vendors tend to call digital measures they provide digital biomarkers)
Example of how digital endpoint could be used to detect a drug effect, vs PBO, and vs an active comparator
Schematic of how digital endpoint can be used for predictor analyses
Algorithms matter - not all are the same, and must be developed for psychiatry use cases
Privacy concerns are highly relevant in implementation of passive monitoring technologies (this set of screenshot shows from a subject's perspective, it may feel like their phone is being taken over by a pharm company)
